Medical Imaging and Advanced Knowledge Technologies (MIAKT), is a joint initiative between the AKT Interdisciplinary Research Collaboration (IRC), specialising in knowledge technologies for the management and synthesis of appropriate information and knowledge content, and the Medical Imaging and Signals (MIAS) IRC, specialising in the intelligent analysis and handling of medical data. The aim of the project is to apply the capabilities of AKT and MIAS to collaborative medical problem solving using knowledge services provided via the e-Science Grid infrastructure.